Here comes Michael

* credits to Phillip Boa.
Born and raised in Pfaffenhofen, Bavaria/Germany.

Current occupation

since 2015 Senior Biostatistician at NEXUS Personalized Health Technologies, a technology platform at ETH in Zurich, Switzerland.
Topic: Advancing translational medicine and personalized health with biostatistics and artificial intelligence.

Professional experiences

2012 - 2015 Senior Scientist at F. Hoffmann-La Roche Ltd., Basel, Switzerland. Pharma Research & Early Development (pRED), Small Molecule Research, Discovery Technologies, Phenotypic Drug Discovery & Target Identification. Topic: High Content Screening (HCS), Image analysis, Biostatistics.
2007 - 2012 Scientist at F. Hoffmann-La Roche Ltd., Basel, Switzerland. Pharma Research & Early Development (pRED), Small Molecule Research, Discovery Technologies, Assay Development & High-Throughput Screening (AD&HTS). Topic: High Content Screening (HCS), Image analysis, Biostatistics.
2003 - 2007 Post-doc with Horst Vogel, Laboratoire de chimie physique des polymères et membranes (LCPPM), Institut de Sciences et Ingénierie Chimiques (ISIC), Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland. Topic: Single-molecule studies of signaling proteins in living cells, i.e. G-protein coupled receptors and nuclear hormone receptors; Single Particle Tracking (SPT) and Fluorescence Correlation Spectroscopy (FCS).
2001 - 2002 Post-doc in the nano-optics group of V. Sandoghdar, Physical Chemistry Laboratory, ETH Zürich, Switzerland. Topic: Single-molecule studies of protein function & dynamics.

Education

2005 - 2007 Diploma of advanced studies in applied statistics, Seminar for Statistics, Department of Mathematics, Swiss Federal Institute of Technology (ETH), Zürich, Switzerland. Thesis: The p-value distribution in genome expression profiling.
1998 - 2001 Graduate student in the group of U.P. Wild, Physical Chemistry Laboratory, ETH Zürich, Switzerland. Projects: single molecule identification; optical polarization tomography of single molecules; dynamics of single membrane proteins. Thesis title: Multi-parameter Fluorescence Spectroscopy: Illuminating single proteins [Reprint - PDF] (7.34MB)
1997 - 1998 Diploma in physics. Thesis: Force spectroscopy on single polymer molecules with optical tweezers. The work was supervised by E.-L. Florin and done in the Light Microscopy Group of E.H.K. Stelzer and the Local Probes Group of J.K.H. Hörber at the European Molecular Biology Laboratory (EMBL) Heidelberg, Germany.
1995 - 1996 Study of physics at Edinburgh University, Scotland (non-graduating) 
1994 - 1998 Study of physics at Heidelberg University, Germany (final degree)
1992 - 1994 Study of physics at Regensburg University, Germany (first degree)

Scientific interests 

Personalized & translational medicine;
Single-cell & multi-omics analysis;
Applied biostatistics & high-dimensional data analysis;
Quantitative image analysis & High-Content Screening;
Super-resolution microscopy & single-molecule spectroscopy.

Teaching experience

Supervising graduate and undergraduate students.
Seminar and lectures on Good practice in high-throughput experiments.
Lecture on Quantitative Big Imaging: From Images to Statistics.
Lecture on "Single-molecules on living cells" for graduate students.
Seminar and lecture series on "Nanobiotechnology and Biophysics".
Tutorials and laboratory courses in physical chemistry and physics.

Patents

"Method for testing a substance interacting with a target molecule"
Hanna Jankewics, Michael Prummer and Horst Vogel
WO2006013109 (09 Feb 2006, priority date 06 Aug 2004).

SCREENING ASSAYS FOR THE IDENTIFICATION OF BACE2 INHIBITORS
BEAUCHAMP, Jeremy; DOEBELI, Heinz; MATILE, Hugues; MIGLIORINI, Cristiano; PRUMMER, Michael; SALVIONI, Paolo; WANG, Haiyan.
WO2010063640, CA2743736A1, CN102227506A, EP2373806A1, US20110229922 (10 Jun 2010, priority date 02 Dec 2008).

"Method for examining multiple cultured cells for presence of periodic structures of target component contained in cultured cells, involves determining presence or absence of periodic structures of target component contained in fixed cells"
PRUMMER, Michael
WO2015067628, EP2871461A1 (14 May 2015, priority date 06 Nov 2013).

Publications

Important notice: These articles have been copyrighted by the respective journals. When you download a copy, it is your duty to comply with any applicable rule. In particular, the per-copy fee indicated in the code on the first page has to be paid through the copyright clearance center. If you don't know how to handle this, we will send you a regular copy by regular mail.

See also my ORCID or PUBLONS page.

29. The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support
A Irmisch et al. Tumor Profiler Consortium.
Cancer Cell 39(3), 288-93 (2021). [Article]

28. SCIM: universal single-cell matching with unpaired feature sets.
Stark SG et al. Tumor Profiler Consortium.
Bioinformatics 36(S2), i919–i927 (2020). [Article]

27. Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice
N Caduff et al.
PLOS Pathogens 16(12), e1009167 (2020). [Article]

26. Machine learning-powered antibiotics phenotypic drug discovery
S Zoffmann et al.
Scientific Reports 9(1), 5013 (2019). [Article]

25. Enhancing gene set enrichment using networks
Michael Prummer
F1000Research 8, 129 (2019). [Article]

24. A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer
L D'Amico, U Menzel, M Prummer et al.
Journal for ImmunoTherapy of Cancer 7, 16 (2019). [Article]

23. Combined Vhl, Trp53 and Rb1 mutation causes clear cell renal cell carcinoma in mice
S Harlander, D Schönenberger, NC Toussaint, M Prummer, A Catalano, L Brandt, H Moch, PJ Wild and IJ Frew
Nature Medicine 23(7), 869-877 (2017). [Article]
See also: News and Views by Schmidt & Linehan.

22. Molecular Phenotyping Combines Molecular Information, Biological Relevance, and Patient Data to Improve Productivity of Early Drug Discovery.
FM Drawnel et al.
Cell Chemical Biology 24(5), 624-634 (2017). [Article]
With a preview by Genentech's John Moffat.

21. MiR-99b-5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients
Lukamowicz-Rajska M, Mittmann C, Prummer M, Zhong Q, Bedke J, Hennenlotter J, Stenzl A, Mischo A, Bihr S, Schmidinger M, Vogl U, Blume I, Karlo C, Schraml P, Moch H
Oncotarget 7(48), 78433-78447 (2016). [Article]

20. Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells
C Patsch et al.
Nature Cell Biology 17(8), 994-1003 (2015). [Article]

19. White-to-brown metabolic conversion of human adipocytes by JAK inhibition
A Moisan et al.
Nature Cell Biology 17(1), 57-67 (2015). [Article]

18. Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells
Drawnel FM, Boccardo S, Prummer M et al.
Cell Reports 9(3), 810-820 (2014). [Open Access]

17. A Random Motility Assay based on Image Correlation Spectroscopy
Michael Prummer, Dorothee Kling, Vanessa Trefzer, Thilo Enderle, Sannah Zoffmann, Marco Prunotto
Biophysical Journal 104, 2362-2372 (2013). [Article]

16. Hypothesis testing in high-throughput screening for drug discovery
Michael Prummer
Journal of Biomolecular Screening 17, 519-529 (2012). [Full Article - PDF] (2'435K)

15. Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass
D Esterhazy et al.
Cell Metabolism 14, 365-377 (2011). [Full Article - PDF] (1'048K)

14. Real time cellular impedance measurements detect Ca2+ channel dependent oscillations of morphology in human H295R adrenoma cells
Athanasios Denelavas, Franziska Weibel, Michael Prummer, Alexander Imbach, Roger G Clerc, Christian M Apfel, Cornelia Hertel
Biochim Biophys Acta - Molecular Cell Research 1813, 754-762 (2011). [Full Article - PDF] (2'093K)

13. Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo
Uhles S, Wang H, Bénardeau A, Prummer M, Brecheisen M, Sewing S, Tobalina L, Bosco D, Wollheim CB, Migliorini C, Sebokova E
Diabetes, Obesity and Metabolism 13, 326-336 (2011). [Full Article - PDF] (1'666K)

12. Bulk measurements cannot probe the survival time distribution of a fluorophore
Michael Prummer and Matthias Weiss
Physical Review E 74, 021115 (2006). [Full Article - PDF] (263K)

11. Visualizing odorant receptor trafficking in living cells down to the single-molecule level
Valérie Jacquier, Michael Prummer, Jean-Manuel Segura, Horst Pick, and Horst Vogel
Proceedings of the National Academy of Science (USA) 103, 14325-14330 (2006). [Full Article - PDF] (1'994K)

10. Multifunctional Lipid/Quantum Dot Hybrid Nanocontainers for Controlled Targeting of Live Cells
Gopakumar Gopalakrishnan, Christophe Danelon, Paulina Izewska, Michael Prummer, Pierre-Yves Bolinger, Isabelle Geissbühler, Davide Demurtas, Jacques Dubochet, and Horst Vogel
Angewandte Chemie International Edition 45, 5478-5483 (2006). [Full Article - PDF] (407K)

9. Posttranslational covalent labeling reveals heterogeneous mobility of individual G protein-coupled receptors in living cells
Michael Prummer, Bruno H. Meyer, Raphael Francini, Jean-Manuel Segura, Nathalie George, Kai Johnsson, and Horst Vogel
ChemBioChem 7, 908-911 (2006). [Full Article - PDF] (189K)

8. Diffusion-time distribution analysis reveals characteristic ligand-dependent interaction patterns of nuclear receptors in living cells
Hanna Jankevics, Michael Prummer, Paulina Izewska, Horst Pick, Kirsten Leufgen, and Horst Vogel
Biochemistry 44, 11676-11683, (2005). [Full Article - PDF] (232K)

7. Multiparameter Microscopy and Spectroscopy for Single-Molecule Analytics
Michael Prummer*, Beate Sick*, Alois Renn, and Urs P. Wild
Analytical Chemistry 76, 1633-1640 (2004). [Full Article - PDF] (336K)

6. Three-Dimensional Optical Polarization Tomography of Single Molecules
Michael Prummer, Beate Sick, Bert Hecht, Urs P. Wild
Journal of Chemical Physics 118, 9824-9829 (2003). [Full Article - PDF] (853K)

5. The citrate carrier CitS probed by single-molecule fluorescence spectroscopy
Christopher N. Kästner*, Michael Prummer*, Beate Sick*, Alois Renn, Urs P. Wild, and Peter Dimroth
Biophysical Journal 84, 1651-1659 (2003). [Full Article - PDF] (289K)

4. Orientation dependence of fluorescence lifetimes near an interface
Maximilian Kreiter, Michael Prummer, Bert Hecht, and Urs P. Wild
Journal of Chemical Physics 117, 9430-9434 (2002). [Full Article - PDF] (144K)

3. Coupled rotation within single F0F1 enzyme complexes during ATP synthesis or hydrolysis
Georg Kaim*, Michael Prummer*, Beate Sick*, Gert Zumofen, Alois Renn, Urs P. Wild, and Peter Dimroth
FEBS Letters 525, 156-163 (2002). [Full Article - PDF] (560K)

2. Single-Molecule Identification by Spectrally and Time-Resolved Fluorescence Detection
Michael Prummer, Christian G. Hübner, Beate Sick, Bert Hecht, Alois Renn, and Urs P.Wild
Analytical Chemistry 72, 443-447 (2000). [Full Article - PDF] (128K)
Note the misprint in eq. 4: both summations over the photon number j need to be replaced by products.

1. Three-Dimensional High-Resolution Particle Tracking for Optical Tweezers by Forward Scattered Light
A. Pralle, M. Prummer, E.-L. Florin, E.H.K. Stelzer, J.K.H. Hörber
Microscopy Research and Techniques 44, 378-386 (1999). [Full Article - PDF] (375K)

*These authors contributed equally to this work.
 

Book chapters

"Mobility and Signaling of Single Receptor Proteins"
Michael Prummer and Horst Vogel
in: Single Molecules and Nanotechnology, Springer Series in Biophysics vol. 12, pp. 131-162, Springer Verlag, Germany 2008.

"Single Molecule Biophysics with Fluorescence"
Michael Prummer and Christian Huebner
in: Handbook of Molecular Biophysics - Methods and Applications, Henrik G. Bohr (ed.), pp. 641-669, Wiley-VCH Verlag, Germany 2009.

Talks

Diabetic Cardiomyopathy in a dish - hiPS cells as in vitro models for precision medicine
Seminar talk invited by Niko Beerenwinkel, Computational Biology group, Department of Biosystems Science & Engineering, 21.10.2015, ETHZ Basel, CH.

Single Cell phenotyping for disease modeling and drug discovery
Seminar talk invited by Dimitrios Stamou, Lundbeck Foundation Center for Biomembranes in Nanomedicine, Faculty of Health and Medical Sciences & Nano-Science Center, 17.07.2015, University of Copenhagen, DK.

Image Correlation Spectroscopy for Phenotypic High Content Screening
Focus on Microscopy FOM 2014, 13.-16.04.2014, Sydney University, Sydney, AUS.

A label-free cell motility assay based on Image Correlation Spectroscopy
Invited talk at the 8th High Content Analysis, Cambridge Healthtech Institute, 08.-11.01.2013, The Fairmont Hotel, San Francisco, US.

A cell motility assay based on Image Correlation Spectroscopy
Invited talk at the 15th MipTec Conference, 24.-27.09.2012, Basel, CH.

Phenotypic High Content Screening Finding the Noughts and Crosses in and of cells
Invited talk at the BioFocus workshop "Discovery Through High Content Screening", 19.04.2012, Hilton Hotel, Basel, CH.

Single-molecule experiments in industry - just a dream or the next breakthrough?
Invited talk at the DPG school on physics "Single Molecule Spectrosopy", German Physical Society, 18.-23.09.2011, Physikzentrum Bad Honnef, D.

Automation of early genotoxicity predictions in non-adherent cells by image-based screening
Invited talk at the 1st Swiss Image-Based Screening Conference, 28.-29.09.2010, EPFL Lausanne, CH.

Hypothesis testing in large datasets: the p-value distribution in high-throughput screening
Platform presentation at the 13th MipTec Conference, 20.-24.09.2010, Basel, CH.

Early genotoxicity prediction in non-adherent cells by automated high-content microscopy
Invited talk at the 8th High Content Analysis, Cambridge Healthtech Institute, 11.-14.01.2010, The Fairmont Hotel, San Francisco, US.

Der Einsatz von zellulären Tests und nichtparametrischer Regression zur Reduktion von Tierversuchen in der Pharmazeutischen Forschung
Alumni Seminar, invited by Werner Stahel, Postgraduate Course in Applied Statistics, Seminar for Statistics, 09.03.2009, ETH Zürich, CH.

Biophotonics - shedding light on single proteins
Colloquium, invited by Lluis Torner, Institut de Ciences Fotoniques (ICFO), 23.11.2007, Barcelona, E.

Protein mobility in cell signaling reactions at the single molecule level
Colloquium, invited by Thilo Enderle, Assay Development & High Throughput Screening, F. Hoffmann-La Roche Ltd., 29.06.2007, Basel, CH.

Cell signaling at the single molecule level (invited)
Latsis Symposium 2007 - Optical Trapping for Molecular Interactions, 25.-27.06.2007, EPFL, Lausanne, CH.

Cellular reactions by single-molecule spectroscopy (invited)
Photonics Day, NCCR Quantum Photonics & Swiss Optical Society, 24.11.2006, EPFL, Lausanne, CH.

Cell signaling and nanomechanics of single proteins
Colloquium, invited by Klaus Meerholz, University of Köln, and Benjamin Kaupp, Jülich Research Institute, 18.09.2006, Jülich, D.

LSM 510 Meta Confocor 3 (instrument demonstration)
3rd Zeiss Live Cell Imaging Workshop, Center for Integrative Genomics, 10.05.2006, Lausanne, CH .

Illuminating biological nano-machines with single-molecule spectroscopy
Colloquium, invited by Ian Campbell, Department of Biochemistry, 10.01.2006, Oxford University, UK.
Seminar talk, invited by Matthias Weiss, German Cancer Research Institute (DKFZ), 04.04.2006, Heidelberg, D.

Single Molecule Spectroscopy: Illuminating Protein Dynamics and Interactions
Seminar talk, invited by Petra Schwille, Institut für Biophysik/BioTec, 13.06.2005, TU Dresden, Germany,
Colloquium, invited by Jörg Wachtrupp, 3. Physikalisches Institut, 05.07.2005, Universität Stuttgart, Germany.

Elucidating cellular signalling by imaging single molecules (invited)
Bi-annual meeting of the German Biophysical Society, 05.-05. – 08.05.2005, Hünfeld, Germany.

Multi-Parameter Fluorescence Spectroscopy: Illuminating Single Biomolecules
Colloquium, invited by Wolfgang Maier, Institute of Physical Chemistry, 05.04.2005, University of Basel ,Switzerland. 

Single Molecule Fluorescence Spectroscopy: Elucidating Protein Dynamics and Interactions
Colloquium, invited by Thomas. Kiefhaber, Biozentrum, 19.04.2005, University of Basel, Switzerland.

Tracking of individual G-protein coupled receptors on living cells
Michael Prummer, Bruno H. Meyer, Raphael Francini, Jean-Manuel Segura, and Horst Vogel
Talk given at the annual meeting of the German Physical Society (DPG), 04.-09.03.2005, Berlin, Germany.

Investigating nuclear receptor interactions in vivo with diffusion time distribution analysis
Michael Prummer, Hanna Jankevics, Paulina Izewska, Horst Pick, Kirsten Leufgen, and Horst Vogel
Platform presentation at the 49th Annual Meeting of the Biophysical Society, 12.-16.02.2005, Long Beach, USA.

Monitoring individual neurokinin-1 receptors on living cells
Talk given at the LCPPM autumn school “Biomolecular interactions on the micro- and nanometer scale”,
20.09.-24.09.2004, Rosenlaui, Switzerland.

Optical Polarization Tomography: A new method to determine the three-dimensional orientation of single molecules
Michael Prummer, Horst Vogel, Beate Sick, Bert Hecht, Urs P. Wild
Talk given at the annual meeting of the German Physical Society (DPG), 08.-12.03.2004, Regensburg, Germany.

Probing individual F0F1 ATP synthases by multi-parameter fluorescence spectroscopy
Michael Prummer, Horst Vogel, Beate Sick, Alois Renn, Gert Zumofen, Urs P. Wild, Georg Kaim, Peter Dimroth
Talk given at the annual meeting of the German Physical Society (DPG), 08.-12.03.2004, Regensburg, Germany.

Multi-parameter fluorescence spectroscopy of single molecules: Take everything a photon can give
Seminar talk, invited by M. Arndt and A. Zeilinger, Institute for Experimental Physics, 04.02.2003, Vienna University, Austria.
Physikalisches Kolloquium, invited by M. Radmacher, Institut für Biophysik, 21.10.2003, Universität Bremen, Germany.

Multi-parameter confocal microscopy and time-resolved emission spectroscopy of single molecules
Michael Prummer, Beate Sick, Alois Renn, Urs P. Wild
Talk presented at the 5th Annual Winter Workshop, 31.01.-03.02.2003, Linz, Austria.

Illuminating Single Proteins by Multi-Parameter Fluorescence Spectroscopy
Seminar talk, invited by M. Auer, Novartis Research Institute, 11.10.2002, Vienna, Austria.

OBSERVING SINGLE F0F1 ATP SYNTHASES AT WORK
Michael Prummer, Beate Sick, Alois Renn, Urs P. Wild, Georg Kaim, Christopher Kaestner, Peter Dimroth
Platform presentation at the 46th Annual Meeting of the Biophysical Socienty, 23.-27.02.2002, San Francisco, CA.
Seminar talk, invited by J. Crain and P. Ghazal, COSMIC seminar & GTI, 10.02.2003, Edinburgh University, UK.

Observing single F0F1 during ATP synthesis
Michael Prummer, Beate Sick, Alois Renn, Urs P. Wild, Georg Kaim, Christopher Kaestner, Peter Dimroth
Seminar talk, invited by T. Nilssen, European Molecular Biology Laboratory (EMBL), 16.08.2001, Heidelberg, Germany.

Three-Dimensional Optical Polarization Tomography of Single Molecules
Michael Prummer, Bert Hecht, Urs P. Wild
Talk given at the Sci & Ski Seminar 2000, 20.03.-24.03.2000, Engelberg, Switzerland, organized by the Wild-Group.

Prospects in Single Molecule Biochemistry
Seminar talk, invited by F.U. Hartl, Cellular Biochemistry,  Max-Planck-Institute for Biochemistry, 13.08.1999, Martinsried, Germany,
Seminar talk, invited by B. Bukau, Biochemistry & Molecular Biology, 17.04.2000, Freiburg University, Germany.

The Elasticity of Single Molecules and 3d Scanning Probe Microscopy - a Task for Optical Tweezers
M. Prummer, E.-L. Florin, E.H.K. Stelzer, J.K.H. Hörber
Seminar talk, invited by T. Geisel, Non-linear dynamics group, Max-Planck-Institute for Fluid Dynamics, 13.09.1999, Gottingen, Germany.

Selected Posters

scROSHI – single cell robust supervised hierarchical identification of cell types
Michael Prummer, Anne Bertolini, Lars Bosshard, Marcus Lindberg, TUMOR PROFILER CONSORTIUM, Daniel Stekhoven, and Franziska Singer
EMBO virtual symposium on The Identity and Evolution of Cell Types, 04-07 May 2021, EMBL, Heidelberg, Germany.

Deciphering single-cell heterogeneity in melanoma for clinical decision support
Michael Prummer, Franziska Singer, Anne Richter, Katja Eschbach, Christian Beisel, Anja Irmisch, Mitch P. Levesque, Mustafa A. Tuncel, Jack Kuipers, Niko Beerenwinkel
CSHL Symposium on BIOLOGICAL DATA SCIENCE, 07-10 Nov 2018, Cold Spring Harbor, US; and at Ascona Workshop on Statistical Challenges in Medical Data Science, 16-21 June 2019, Centro Congressi Stefano Franscini, Ascona, CH. and at WelcomeTrust virtual conference on Single Cell Biology, 09-12 Nov 2020, Wellcome Genome Campus, Hinxton, UK.

Improving gene set analysis using networks
Michael Prummer
CSHL Symposium on SYSTEMS BIOLOGY: NETWORKS, 14.-18.03.2017, Cold Spring Harbor, US; and at the 3rd International SystemsX.ch Conference on Systems Biology, 04.-07.09.2017, ETH Zurich, CH; and at the SIB days 2018, Biel, CH; and at ISMB/ECCB 2019, Basel, CH.
F1000Research 2019, 8(ISCB Comm J):1296 (poster) (doi: 10.7490/f1000research.1117220.1)

TCGAbrowser: a self-service all-cancer multi-platform real-time analysis framework
Phil Cheng, Michael Prummer, Reinhard Dummer, Mitch Levesque and Daniel Stekhoven
LXXXI CSHL Symposium on Quantitative Biology: TARGETING CANCER, 01.-05.06.2016, Cold Spring Harbor, US.

NEXUS: supporting personalized medicine with state-of-the art technologies
Franziska Singer, Michael Prummer, Daniel Stekhoven, Miquel Busquets Lopez, Christian Stirnimann
EMBL Stanford Conference: Personalised Health, 16.-19.11.2015, Heidelberg, DE.

Image Correlation Spectroscopy for High Throughput Single Cell Analysis
Michael Prummer
EMBL Symposium: Seeing is Believing - Imaging the Processes of Life, 06.-10.10.2015, Heidelberg, DE.

Single Cell Image Correlation Analysis and Phenotypic Screening for Diabetic Cardiomyopathy
Michael Prummer, Faye Drawnel, Frederic Delobel, Jacques Bailly, Roberto Iacone
Biophysical Society 59th Annual Meeting, 07.-11.02.2015, Baltimore, US. doi:10.1016/j.bpj.2014.11.1762 and at the 3rd Swiss Image-Based Screening Conference, 30.09.-01.10.2015, Basel, CH.

AN AUTOMATED LABEL-FREE RANDOM CELL MOTILITY ASSAY BASED ON IMAGE CORRELATION SPECTROSCOPY
Michael Prummer, Dorothee Kling, Vanessa Trefzer, Thilo Enderle, Sannah Zoffmann
Biophysical Society 56th Annual Meeting, 25.-29.02.2012, San Diego, US, doi:10.1016/j.bpj.2011.11.1046 and at the 2nd Swiss Image-Based Screening Conference, 10.-11.06.2013, Lausanne, CH.

In-vitro toxicity profiling in arrays of non-adherent cells by automated high-content microscopy
Michael Prummer, Roger Werder, Sannah Zoffmann, Thilo Enderle, Rene Rietmann, Dieter Vögelin, Patrick Iaiza, Christof Fattinger, Michael Hennig, Stephan Kirchner, Sabine Müller, Joelle Muller, Claudia McGinnis, Kyle Kolaja, Thomas Weiser
Annual Meeting of the American Society for Cell Biology, 11.-15.12.2010, Philadelphia, US,

Tracking the scent: functional mobility of odorant receptors
Michael Prummer, Valerie Jacquier, Horst Pick, Horst Vogel
Frontiers in Chemical Biology: Single Molecules, The Royal Society of Chemistry, 26.-29.03.2006, Cambridge, UK.

Investigating hormone receptor interactions in vivo with diffusion time distribution analysis
Michael Prummer, Hanna Jankevics, Horst Vogel
NRP 50 annual meeting “Endocrine Disruptors: Relevance to Humans, Animals and Ecosystems“,
10.-12.10.2004, Gurten, Bern, Switzerland.

Multi-parameter fluorescence spectroscopy of single dye-conjugated F0F1 ATP synthases
Michael Prummer, Beate Sick, Georg Kaim, Alois Renn.
Poster presented at the International Symposium "Elucidating biomolecular networks by single-molecule technologies", 26.-31.10.2003, Monte Verita, Ascona, Switzerland.

Observing single F0F1 ATPases at work
Michael Prummer, Beate Sick, Alois Renn, Urs P. Wild, Georg Kaim, Christopher Kaestner, Peter Dimroth
4th International Conference on Biological Physics, 30.07.- 03.08.2001, Kyoto, Japan

Hochauflösende dreidimensionale interferometrische Positionsdetektion in der Photonischen Kraftmikroskopie
M. Prummer, A. Pralle, E.-L. Florin, E. H. K. Stelzer und J. K. H. Hörber
Poster presented at the workshop "Scanning-Probe-Microscopies and Organic Materials VII, 07.-09.10.1998, Berlin, Germany.


Last modified: 12.04.2016 by Michael Prummer.