Real-Time Organ Assessment
To minimize ischemia related complications in solid organ transplantation, we have developed a method to measure mitochondrial damage prior to transplantation in real time. A sensor prototype was used to assess extended criteria liver grafts and allowed for discrimination of organs, that were not suitable for transplant.
Read more at:Huwyler et al. A Spectrofluorometric Method for Real-Time Graft Assessment and Patient Monitoring. Advanced Science (2023)
Eden et al. Screening for mitochondrial function before use-routine liver assessment during hypothermic oxygenated perfusion impacts liver utilization. eBioMedicine (2023)
When engineering meets surgery: Development of the first clinical prototype